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Senior Scientist, Lead Downstream Process Development, Biosyntia / 1851/CLOSED

The Company
Biosyntia is an industrial biotech company developing bio-based manufacturing processes with all critical capabilities for success in-house – stretching from microbial engineering, fermentation optimization, product purification, formulation to sales. Biosyntia focuses especially on developing more natural and sustainable processes for active ingredients used in beauty and nutrition such as vitamins, antioxidants, and similar ingredients. The company has developed proprietary technologies such as Biosynthetic Selections™, which dramatically reduce the risk, cost, and time for developing fermentation processes. The company has won more than 15 recognition awards, including being one of the most innovative SMEs in Europe. Today the company employs 20 scientists and business developers, who operate from Biosyntia’s lab and offices in Copenhagen, Denmark. See more at

The Culture
Biosyntia is a growing organization, and you will be encouraged and welcomed to bring forth new ideas, discuss concerns and share feed-back with colleagues and management. Biosyntia leverages the effectiveness of an agile working environment, when possible, for the betterment of employee work-life balance. They work as one team and like to celebrate their successes and spend time together at social events.

Senior Scientist, Lead Downstream Process Development

  • One of the most innovative SMEs in Europe
  • Developing more natural sustainable processes for active ingredients
  • You have potential to become a team leader

The Challenge
You will be responsible for the development of scale-up and scale-down methods and models to provide predictive process parameters for manufacturing scale and cost analysis. You will spend 60% of your time in the laboratories and be supported by initially one Technician. The team is expected to grow as the company matures and you have the ambition and potential to become Team Leader.

The position requires interactions with several disciplines and partners, including analytical chemistry, strain engineering, and external partners such as CMO’s and collaboration partner companies. You are expected to communicate on all levels and like to be involved with both commercial and science people.

Technology transfers and CMO support may be required during some periods, so you also enjoy 20% traveling.

Areas of responsibility:

  • Perform downstream processing (DSP) experimentation at lab scale to support commercially scalable process definition and development
  • Analyze and interpret data to develop models for predictive performance and cost
  • Conduct DSP process development at bench and pilot scale, transfer processes to commercial scale, and support initial commercial scale production
  • Conduct process and/or equipment testing at CRO/CMO and equipment vendor facilities
  • Manage technology transfer between Biosyntia and CRO/CMO (from lab scale to pilot scale to manufacturing scale)
  • Support development of techno-economic analyses for new fermentation processes
  • Prepare estimated CAPEX for equipment modifications, and generate capital and variable cost estimates for purification processes
  • Analyze and present data to fellow scientists and external companies and partners

Biosyntia has focus on teamwork. You must share knowledge, be curious, ask questions and learn new things to achieve goals and work with ambitious deadlines. You will be rewarded by focusing on teamwork and making brilliant results through and together with the rest of the team. If you can recognize yourself in this description, you might be the next brilliant Senior Scientist, Lead Downstream Process Development Process Development to support the expanding portfolio and the continued global growth of Biosyntia.

Your Talent
You have a MSc or PhD in Chemical Engineering or relevant field and + 5 years of relevant industry experience. The ideal candidate should have experience from bench scale, pre-pilot (10-30L), pilot (>1000L) and manufacturing scale (>10m3) and have hands-on experience with various unit operations.

The successful candidate will have the following profile:

  • Experience with a range of commercially applicable unit operations such as cell isolation, extraction, liquid-liquid and liquid-solid separations, anion exchange, distillation, drying, filtration, crystallization, chromatography, etc.
  • Demonstrated experience in developing DSP separation and purification processes for small molecules in fermentation broth
  • Demonstrated experience in scaling processes from lab to pilot or plant scale, including performing on-site support
  • Demonstrated experience in performing tech-transfer from/to CMO including writing the required reports
  • Thorough knowledge of chemical engineering principles and familiarity with fermentation and biochemical processes
  • Excellent communication and interpersonal skills due to cross collaborative nature of the role

You have a proactive mindset and a desire to continuously develop and find innovative solutions. In addition, you are well-organized, and can plan, execute, and meet deadlines. You have the ability to work successfully under pressure in a fast-paced environment and with tight timelines.

As an open-minded dedicated and flexible person, you utilise your high level of energy and can-do attitude to proactively handle the various tasks at hand.

Strong communication skills are essential in this role, which interacts with other disciplines, and you are of course excellent in English, both written and verbal.

Best Talent is responsible for the recruitment process for this position at Biosyntia and reviews your application on a confidential basis. Forward your application including your CV attention ”1851/Sr. Scientist, Lead Downstream ” by way of e-mail to You can read more about Best Talent at bruger cookies. For at give dig en bedre oplevelse gemmer vi informationer om dit besøg. OK